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To our customers: if you would like to inform us about your publications in which MIA's measurement software was used, please email us at support@mia-llc.com

Partial list of institutions referenced:

Academic Medical Center, Amsterdam, The Netherlands Boston University Medical Center
Brigham and Women’s Hospital – Harvard Medical School Framingham Study
Medical College of Georgia Penn State University
University of British Columbia University of California San Francisco
Universitatsklinikum Dusseldorf University of Iowa
University of Mainz The Chinese University of Hong Kong

Partial list of research publications in which Vascular Tools were used to generate quantitative vascular ultrasound measurements, sorted by the publication date:

  1. Dominik Schuler, Roberto Sansone, Till Freudenberger, Ana Rodriguez Mateos, Gesine Weber, Tony Momma, Christine Goy, Joachim Altschmied, Judith Haendeler, Jens Fischer, Malte Kelm, and Christian Heiss. Measurement of Endothelium-Dependent Vasodilation in Mice.Arteriosclerosis, Thrombosis, and Vascular Biology. 2014
  2. Cudmore S, de Groot E, O’Kennedy N. Food Health Claims - Cardiovascular Health. Atlantia Food Clinical Trials. 2014
  3. Billinger SA, Mattlage AE, Ashenden AL, Lentz AA, Harter G, Rippee MA. Aerobic exercise in subacute stroke improves cardiovascular health and physical performance. J Neurol Phys Ther. 2012 Dec;36(4):159-65. Awarded manuscript of the year.
  4. Dick H. J. Thijssen, Mark A. Black, Kyra E. Pyke, Jaume Padilla, Greg Atkinson, Ryan A. Harris, Beth Parker, Michael E. Widlansky, Michael E. Tschakovsky and Daniel J. Green. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline. Am J Physiol Heart Circ Physiol 300:H2-H12, 2011.
  5. Ann C Skulas-Ray, Penny M Kris-Etherton, William S Harris, John P Vanden Heuvel, Paul R Wagner, and Sheila G West. Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia. Am J Clin Nutr. 2010.
  6. Tinoy J. Kizhakekuttu, David D. Gutterman, Shane A. Phillips, Jason W. Jurva, Emily I. L. Arthur, Emon Das and Michael E. Widlansky. Measuring FMD in the brachial artery: how important is QRS gating? J Appl Physiol 109:959-965, 2010.
  7. Taisto Sarkola, Andrew Redington, Fred Keeley, Timothy Bradley, Edgar Jaeggi. Transcutaneous Very-high-resolution Ultrasound to Quantify Arterial Wall Layers of Muscular and Elastic Arteries:Validation of a Method. Atherosclerosis, 2010.
  8. Patricia H. Davis, Jeffrey D. Dawson, M. Beth Blecha, Rebecca K. Mastbergen, and Milan Sonka. Measurement of Aortic Intimal-Medial Thickness in Adolescents And Young Adults. Ultrasound in Med. & Biol., Vol. 36, No. 4, pp. 560–565, 2010.
  9. Ryan A. Harris, Steven K. Nishiyama, D. Walter Wray and Russell S. Richardson. Ultrasound Assessment of Flow-Mediated Dilation. Hypertension 2010;55;1075-1085
  10. J.D. Dawson, M. Sonka, M.B. Blecha, W. Lin, P. H. Davis: Risk Factors Associated With Aortic and Carotid Intima-Media Thickness in Adolescents and Young Adults: The Muscatine Offspring Study, J Am Coll Cardiol 2009;53:2273–-2279
  11. Cheuk-Man Yu, Qing Zhang, Linda Lam, Hong Lin, Shun-Ling Kong, Wilson Chan, Jeffrey Wing-Hong Fung, Kenny K K Cheng, Iris Hiu-Shuen Chan, Stephen Wai-Luen Lee, John E Sanderson and Christopher Wai-Kei Lam. Comparison of intensive and low-dose atorvastatin therapy in the reduction of carotid intimal–medial thickness in patients with coronary heart disease. Heart 2007;93;933-939; originally published online 7 Mar 2007; doi:10.1136/hrt.2006.102848 http://heart.bmj.com/cgi/content/full/93/8/933
  12. Christian Heiss, MD, Thomas Lauer, MD, André Dejam, MD, Petra Kleinbongard, PHD, Sandra Hamada, MS, Tienush Rassaf, MD, Simone Matern, BS, Martin Feelisch, PHD, Malte Kelm, MD. Aachen and Duesseldorf, Germany; and Boston, Massachusetts. Plasma Nitroso Compounds Are Decreased in Patients With Endothelial Dysfunction. Journal of the American College of Cardiology Vol. 47, No. 3, 2006
  13. Hagen Schroeter, Christian Heiss, Jan Balzer, Petra Kleinbongard, Carl L. Keen, Norman K. Hollenberg, Helmut Sies, Catherine Kwik-Uribe, Harold H. Schmitz, and Malte Kelm. University of California; Heinrich-Heine University; Brigham and Women’s Hospital; Mars Incorporated. Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proceedings of the National Academy of Sciences of the United States of America, January 24, 2006, vol. 103, no. 4. http://www.pnas.org/cgi/content/abstract/103/4/1024
  14. Raaj R. Sankatsing, Eric de Groot, J. Wouter Jukema, Pim J. de Feyter, Dudley J. Pennell, Paul Schoenhagen, Steven E. Nissen, Erik S.G. Stroes and John J.P. Kastelein. Academic Medical Center, Amsterdam, The Netherlands. Surrogate markers for atherosclerotic disease. Current Opinion in Lipidology 2005, 16:434–441
  15. Christian Heiss, MD, Stefanie Keymel, MS, Ulrike Niesler, MS, Jutta Ziemann, BS, Malte Kelm, MD, Christoph Kalka, MD. Düsseldorf, Germany. Impaired Progenitor Cell Activity in Age-Related Endothelial Dysfunction. Journal of the American College of Cardiology. Vol. 45, No. 9, 2005.
  16. Thomas Lauer, Christian Heiß, Michael Preik, Jan Balzer, Dieter Hafner, Bodo. E. Strauer and Malte Kelm. Reduction of peripheral flow reserve impairs endothelial function in conduit arteries of patients with essential hypertension. Journal of Hypertension. Vol 23 No 3, 2005.
  17. Ascan Warnholtz, MD, Mir Abolfazl Ostad, MD, Thomas Heitzer, MD, Britta U. Goldmann, MD, Goetz Nowak, MD, and Thomas Munzel, MD. University of Mainz. Effect of Tirofiban on Percutaneous Coronary Intervention-Induced Endothelial Dysfunction in Patients With Stable Coronary Artery Disease. The American Journal of Cardiology Vol. 95 January 1, 2005.
  18. Mancini GB. Reporting measures of endothelial dysfunction independent of baseline arterial diameter. [Letter] American Journal of Cardiology. 94(9):1222-3, 2004 Nov 1.
  19. Kapuku GK. Treiber FA. Hartley B. Ludwig DA. Gender influences endothelial-dependent arterial dilatation via arterial size in youth. American Journal of the Medical Sciences. 327(6):305-9, 2004.
  20. Hartley B. Treiber F. Ludwig D. Kapuku G. Correlates of femoral artery flow mediated dilation in a multi-ethnic sample of 12- to 26-year-olds. Ethnicity & Disease. 14(2):227-32, 2004.
  21. E. J. Benjamin, M. G. Larson, M. J. Keyes, G. F. Mitchell, R. S. Vasan, J. F. Keaney, B. T. Lehman, S. Fan, E. Osypiuk, J. A. Vita: Clinical Correlates and Heritability of Flow-Mediated Dilation in the Community - The Framingham Heart Study. Circulation, 109:613-619, 2004.
  22. J. A. Vita, J. F. Keaney, M. G. Larson, M. J. Keyes, J. M. Massaro, I. Lipinska, B. T. Lehman, S. Fan, E. Osypiuk, P. W. F. Wilson, R. S. Vasan, G. F. Mitchell, E. J. Benjamin: Brachial Artery Vasodilator Function and Systemic Inflammation in the Framingham Offspring Study. Circulation 110:3604-3609, 2004.
  23. G. F. Mitchell, H. Parise, J. A. Vita, M. G. Larson, E. Warner, J. F. Keaney, M. J. Keyes, D. Levy, R. S. Vasan, E. J. Benjamin: Local Shear Stress and Brachial Artery Flow-Mediated Dilation - The Framingham Heart Study. Hypertension, 44:134-139, 2004.
  24. M M Engler, M B Engler, M Malloy, E Chiu, D Besio, S Paul, M Stuehlinger, J Morrow, P Ridker, N Rifai, M Mietus-Snyder: Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY Study. Int J Clin Pharmacol and Therapeut, Vol. 42(12), 672-679, 2004.
  25. Engler MB. Engler MM. Chen CY. Malloy MJ. Browne A. Chiu EY. Kwak HK. Milbury P. Paul SM. Blumberg J. Mietus-Snyder ML. Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults. [Clinical Trial. Journal Article. Randomized Controlled Trial] Journal of the American College of Nutrition. 23(3):197-204, 2004 Jun.
  26. G B J Mancini and D Abbott and C Kamimura and E Yeoh, Validation of a new ultrasound method for the measurement of carotid artery intima medial thickness and plaque dimensions. Can. J. Cardiology, 20: 1355-1359, 2004.
  27. M M Engler; M B Engler, M J Malloy, E Y Chiu, M C Schloetter, S M Paul, M Stuehlinger, K Y Lin; J P Cooke, J D Morrow, P M Ridker; N Rifai, E Miller; J L Witztum, M Mietus-Snyder: Antioxidant Vitamins C and E Improve Endothelial Function in Children With Hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Circulation, 108:1059-1063, 2003.
  28. Christian Heiss, Andre Dejam, Petra Kleinbongard, Tankred Schewe, Helmut Sies, Malte Kelm, Vascular Effects of Cocoa Rich in Flavan-3-ols. Journal of American Medical Association. Vol 290, No. 8. August 27, 2003.
  29. G B Mancini, E Yeoh, D Abbott, and S Chan. Validation of an automated method for assessing brachial artery endothelial dysfunction. Can. J. Cardiology, 18:259-262, 2002.
  30. M. Sonka, W. Liang, and R. M. Lauer. Automated analysis of brachial ultrasound image sequences: Early detection of cardiovascular disease via surrogates of endothelial function. IEEE Trans. Med. Imaging, 21:1271-1279, 2002.
  31. Sammy Chan, G B John Mancini, Suzanne Burns, Kori Kingsbury, Anka Brozic, Frances Johnson, Sandra Barr, Lisa Kuramoto, Michael Schulzer, Jiri Frohlich, and Andrew Ignaszewski. Normal endothelial function attenuates the risks associated with high plaque burden (abstract). Circulation, 104:II-486, 2001.
  32. Geetha Raghuveer, Roger Browning, Christine A Sinkey, Catherine Chenard, Phyllis Stumbo, and William G Haynes. Effects of altering dietary intake of protein on homocysteine and vascular function in hyperhomocysteinemic subjects (abstract). Circulation, 104:II-561, 2001.
  33. Alexei V Agapitov, Marcelo L Correia, Douglas B Segal, Christine A Sinkey, Bradley G Phillips, and William G Haynes. Is sympathetically-mediated vasoconstriction enhanced in normotensive humans with obesity? (abstract). Circulation, 104:II-391, 2001.
  34. S G West. Effect of diet on vascular reactivity: An emerging marker for vascular risk. Current Atherosclerosis Reports, 3:446-455, 2001.
  35. Noyan Gokce, John F Keaney, James Menzoian, Michael Watkins, David Kahn, Liza Hunter, Stephen J Duffy, and Joseph A Vita. Impaired brachial artery endothelial function predicts perioperative cardiovascular events in patients undergoing vascular surgery (abstract). Circulation, 104:II-328, 2001.
  36. David S Bader, Noyan Gokce, Helene Glassberg, Debra Sherman, Peter L Swerdloff, Carol O'Malley, John F Keaney, Joseph A Vita, and Gary J Balady. Effects of exercise on upper and lower extremity endothelial function in patients with coronary artery disease (abstract). Circulation, 104:II-343, 2001.
  37. Marguerite M Engler, Mary B Engler, Mary J Malloy, Monique C Schloetter, Jason D Morrow, and Michele L Mietus-Snyder. The effects of nutritional counseling and vitamins c and e on endothelial function, lipids and isoprostane levels in hyperlipidemia: Endothelial assessment of risk from lipids in youth (EARLY) study (abstract). Circulation, 104:II-470, 2001.
  38. A J Maxwell, B Anderson, M P Zapien, and J P Cooke. Endothelial dysfunction in hypercholesterolemia is reversed by a nutritional product designed to enhance nitric oxide activity. Cardiovascular Drugs & Therapy, 14:309-316, 2000.
  39. M Preik, T Lauer, C Heiss, S Tabery, B E Strauer, and M Kelm. Automated ultrasonic measurement of human arteries for the determination of endothelial function. Ultraschall in Med., 21:1-5, 2000.
   
 
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Vascular Tools 5- FDA Approved - clinical assesment of FMD/endothelial function of brachial artery and IMT/intimal-medial thickness of carotid artery from ultrasound image data.

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